Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0314882
PubChem CID
Molecular Formula
C6H8ClN7O
Molecular Weight
229.631 g/mol
Synonyms/Alias
N/A (Not available)
InChI Key
XSDQTOBWRPYKKA-UHFFFAOYSA-N
InChI
InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)
IUPAC Name
3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

15 15 0 0 0 0 0 0 0 0999 V2000
0.2107 -0.2136 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.6089 1.2326 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.0605 1...

Experimental Data

Activity Data

Target Ion Channel
Acid-sensing ion channel 1
Uniprot Accession Number
Function
inhibitor
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
23.49% at 25 μM

Experimental Conditions

pH
Not mention
Holding Potential
Not specified
Temperature
Not mention
Test Method
Fluorometric Imaging Plate Reader (FLIPR) Membrane Potential Assay
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
15
Rotatable Bonds
1
logP
-1.292
Complexity
56.0071
TPSA (Ų)
159.29
H-Bond Donors
4
H-Bond Acceptors
5
Ring Count
1
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